Cookie Cutter Literature

It's a debate I've had every year in English.

Is there only one story?

Are all books based off of one concept? Even though the setting and plot and characters change, is there only one base story?

I know Chick-Lit gets a lot of criticism for being very cookie-cutter, but a lot of extremely literary people think all books have a bit of Chick-Lit syndrome.

I'd like to know your thoughts. I need more ammo for the next time if comes up in a discussion ;)